There's a phrase in Shakespeare: he refers to it as the 'hidden imposthume', and this idea of a hidden swelling is seminal to cancer. But even in more contemporary writing it's called 'the big C'.
The point is you have to break the ice with viewer.
It remains an astonishing, disturbing fact that in America - a nation where nearly every new drug is subjected to rigorous scrutiny as a potential carcinogen, and even the bare hint of a substance's link to cancer ignites a firestorm of public hysteria and media anxiety - one of the most potent and
Most days, I go home and I feel rejuvenated. I feel ebullient.
I think the way we think about cancer, the way we treat cancer, has dramatically changed in the last century. There is an enormous amount of options that a physician can provide today, right down from curing patients, treating patients or providing patients with psychic solace or pain relief.
Good physicians are rarely dispassionate. They agonize and self-doubt over patients.
I think when we use 'stress', we are often using a kind of dummy word to try to fit many different things into one big category.
Down to their innate molecular core, cancer cells are hyperactive, survival-endowed, scrappy, fecund, inventive copies of ourselves.
Sandeep Jauharâ€™s Doctored is a passionate and necessary book that asks difficult questions about the future of medicine. The narrative is gripping, and the writing is marvelous. But it was the gravity of the problemâ€”so movingly toldâ€”that grabbed and kept my attention throughout this remarkable
It is hard to look at the tumor and not come away with the feeling that one has encountered a powerful monster in its infancy
A breast cancer might turn out to have a close resemblance to a gastric cancer. And this kind of reorganization of cancer in terms of its internal genetic anatomy has really changed the way we treat and approach cancer in general.
I had seen cancer at a more cellular level as a researcher. The first time I entered the cancer ward, my first instinct was to withdraw from what was going on - the complexity, the death. It was a very bleak time.
There is a duality in recognising what an incredible disease it is - in terms of its origin, that it emerges out of a normal cell. It's a reminder of what a wonderful thing a normal cell is. In a very cold, scientific sense, I think a cancer cell is a kind of biological marvel.
When you immerse yourself in medicine you realise that hope is not absolute. It's not that simple.
If the system was not robust enough these fluctuations would have gone unrecorded.
It feltâ€”nearly twenty-five hundred years after Hippocrates had naively coined the overarching term karkinosâ€”that modern oncology was hardly any more sophisticated in its taxonomy of cancer.
History repeats, but science reverberates.
I think the cardinal rule of learning to write is learning to read first. I learned to write by learning to read.
Pharmacology is benefited by the prepared mind. You need to know what you are looking for. Siddhartha Mukhe
I believe the biggest breakthroughs on cancer could come from brilliant researchers based in India.
Cancer's life is a recapitulation of the body's life, its existence a pathological mirror of our own. Susan Sontag warned against overburdening an illness with metaphors. But this is not a metaphor. Down to their innate molecular core, cancer cells are hyperactive, survival-endowed, scrappy, fecund,
There is a very moving and ancient connection between cancer and depression.
All cancers are alike but they are alike in a unique way.
In 2005, a man diagnosed with multiple myeloma asked me if he would be alive to watch his daughter graduate from high school in a few months. In 2009, bound to a wheelchair, he watched his daughter graduate from college. The wheelchair had nothing to do with his cancer. The man had fallen down while
Cancer has enormous diversity and behaves differently: it's highly mutable, the evolutionary principles are very complicated and often its capacity to be constantly mystifying comes as a big challenge.
Probably the most important reason we are seeing more cancers than before is because the population is ageing overall. And cancer is an age-related disease.
Most discoveries even today are a combination of serendipity and of searching. Siddhartha Mukherje
We don't know why, but pancreatic cancer has a very interesting physiological link to depression. There seems to be a deep link, and we don't know what it is.
Most discoveries even today are a combination of serendipity and of searching.
If there's a seminal discovery in oncology in the last 20 years, it's that idea that cancer genes are often mutated versions of normal genes.